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Help prevent bloodstream infections before they start

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Bloodstream infections are a critical issue for health care facilities around the world. Approximately 60% of hospital-acquired bloodstream infections originate from some form of vascular access.1 Some of the most well-known infections are Catheter-Related Bloodstream Infection (CRBSI) and Central Line-Associated Bloodstream Infection (CLABSI).

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Sources of vascular-associated bloodstream infections

Bloodstream infections can be acquired at the time of insertion or anytime throughout the duration of vascular access. However, most happen after insertion.2,3-7 Microbes can enter the bloodstream through extraluminal or intraluminal access points4-8. Contact a representative to learn more about the best practices for presenting bloodstream infections.

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Intraluminal contamination

Results when bacteria migrates through the catheter post insertion, typically via contamination of the lumen through the catheter port¹¹⁻¹².

Extraluminal contamination

Results when bacteria originating on the surface of the skin migrates along the outside of the catheter and enters through the insertion point⁴ ⁹⁻¹⁰.

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Reduce risk at all access points.

Learn more about how you can help protect your patients from bloodstream infections.

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Learn more about bloodstream infection prevention solutions.

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Gloved hands putting a 3M™ Curos™ Disinfecting Port Protector on a port.
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1. Scheithauer S, Lewalter K, Schröder J, Koch A, Häfner H, Krizanovic V, Nowicki K, Hilgers RD, Lemmen SW. Reduction of central venous line-associated bloodstream infection rates by using a chlorhexidine-containing dressing. Infection. 2014 Feb 1;42(1):155-9.
2. Guide to Preventing Central Line-Associated Bloodstream Infections. Association for Professionals in Infection Control and Epidemiology. 2015.
3. Mermel LA, Allon M, Bouza E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009; 49(1): 1-45.
4. Safdar N, Maki DG. The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters. Intensive Care Med. 2004; 30(1): 62-67.
5. Mermel LA. What is the predominant source of intravascular catheter infections? Clin Infect Dis. 2011; 52(2): 211-212.
6. Maki DG, Stolz SM, Wheeler S, Mermel LA. Prevention of central venous catheter-related bloodstream infection by use of an antiseptic-impregnated catheter: A randomized, controlled trial. Ann Intern Med. 1997; 127(4): 257-266.
7. Douard MC, Clementi E, Arlet G, et al. Negative catheter-tip culture and diagnosis of catheter-related bacteremia. Nutrition. 1994; 10(5): 397-404.
8. Dittmer ID, Sharp D, McNulty CA, Williams AJ, Banks RA. A prospective study of central venous hemodialysis catheter colonization and peripheral bacteremia. Clin Nephrol. 1999; 51(1): 34-39.
9. Mermel LA, McCormick RD, Springman SR, Maki DG. The pathogenesis and epidemiology of catheter related infection with pulmonary artery Swan-Ganz catheters: A prospective study utilizing molecular subtyping. Am J Med. 1991; 91(36):197S–205S.
10. Maki DG, Weise CE, Sarafin HW. A semiquantitative culture method for identifying intravenous-catheter-related infection. N Engl J Med. 1977; 296(23): 1305-1309.
11. Segura M, Lladó L, Guirao X, Piracés M, Herms R, Alia C, Sitges-Serra A. A prospective study of a new protocol for ‘in situ’diagnosis of central venous catheter related bacteraemia. Clin Nutr. 1993; 12(2): 103-107. 12. Raad I, Costerton W, Sabharwal U, Sadlowski M, Anaissie E, Bodey GP. Ultrastructural analysis of indwelling vascular catheters: a quantitative relationship between luminal colonization and duration of placement. J Infect Dis. 1993; 168(2): 400-407.

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