3M™ SoluPrep™ Skin Antiseptic being applied to a patient's arm.

3M™ SoluPrep™ Skin Antiseptics

It's the solution that counts.

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Fight surgical site infections with the Canadian market leader, 3M SoluPrep™ Skin Antiseptics.

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    • The first and only skin antiseptics authorized for professional healthcare use.1,2
    • Used by healthcare professionals over 1 billion times.3
  • An icon of a maple leaf.
    • The Canadian market leader4 and available in a range of formats and formulations.
  • An icon of a shield with a cross.
    • Demonstrated efficacy (in vitro and in vivo).2
    • Safety studies showed no irritation or sensitization when applied as directed.5
    • Microbial testing and quality assurance exceed regulatory requirements.6,7,8
  • An icon of an alarm clock.
    • Demonstrates extended persistence.2,5

Can you tell fact from fiction when it comes to skin antiseptics?

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A nurse about to apply 3M™ SoluPrep™ Nasal Antiseptic to a woman's nose.

3M™ SoluPrep™ Nasal Antiseptic

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Featured products

  • 3M™ SoluPrep™ Prefilled Sterile Applicator

    • Helping reduce bacteria on skin to diminish the risk of surgical site infection, 100.24 is indicated for skin antisepsis prior to invasive procedures
    • For hospital and healthcare professional use only
    • Maximum treatment area is 52 cm x 52 cm
    • Antimicrobial persistence of 72 hours
    • Latex free
  • 3M™ SoluPrep™ Sponge

    • For Hospital and Healthcare professional use only
    • Maximum treatment area is 20 cm x 20 cm (1 sponge)
    • Persistence up to 72 hours
    • Latex free
    • Alcohol free
  • 3M™ SoluPrep™ Swab, large

    • 2% w/v chlorhexidine gluconate (CHG) and 70% v/v isopropyl alcohol (IPA)
    • Latex free
    • For use on intact skin prior to invasive procedures

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Find out more about the complexities of skin antiseptics.

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Antiseptics and sterilization methods


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  • 1. As of January 1, 2019, in the Health Canada Drug Product Database.
  • 2. Health Canada Guidance Document: Human-Use Antiseptic Drugs, Ottawa, 2009/11/27.
  • 3,4. Based on 3M™ SoluPrep™ Brand sales data.
  • 5. 3M internal data on file.
  • 6. 3M Canada White Paper: Quality of 3M Canada Skin Antiseptic Drug Products 1805-11949 E, 2018.
  • 7. Health Products and Food Branch Inspectorate. Good Manufacturing Practices (GMP) Guidelines — 2009 Ed. Version 2 (GUI-0001), March 4, 2011.
  • 8. USP <111> Microbiological Examination of Nonsterile Products: Acceptance Criteria for Pharmaceutical Use.
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